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Mouse knockout models for HIV-1 restriction factors
Infection of cells with human immunodeficiency virus 1 (HIV-1) is controlled by restriction factors, host proteins that counteract a variety of steps in the life cycle of this lentivirus. These include SAMHD1, APOBEC3G and tetherin, which block reverse transcription, hypermutate viral DNA and preven...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Basel
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160573/ https://www.ncbi.nlm.nih.gov/pubmed/24854580 http://dx.doi.org/10.1007/s00018-014-1646-8 |