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Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia

Inadequate calorie intake or starvation has been suggested as a cause of neonatal jaundice, which can further cause permanent brain damage, kernicterus. This study experimentally investigated whether additional glucose treatments induce the bilirubin-metabolizing enzyme – UDP-glucuronosyltransferase...

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Detalles Bibliográficos
Autores principales: Aoshima, Naoya, Fujie, Yoshiko, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160704/
https://www.ncbi.nlm.nih.gov/pubmed/25209391
http://dx.doi.org/10.1038/srep06343