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Q&A: targeting autophagy in cancer—a new therapeutic?
Macroautophagy (autophagy hereafter) captures and degrades intracellular proteins and organelles in lysosomes as a quality control mechanism and recycles their components to sustain survival in starvation. Cellular self-cannibalization by autophagy is thought to have a context-dependent role in canc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160717/ https://www.ncbi.nlm.nih.gov/pubmed/25215185 http://dx.doi.org/10.1186/2049-3002-2-14 |