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Targeting regulatory T cells to improve vaccine immunogenicity in early life
Human newborns and infants are bombarded with multiple pathogens on leaving the sterile intra-uterine environment, and yet have suboptimal innate immunity and limited immunological memory, thus leading to increased susceptibility to infections in early life. They are thus the target age group for a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161046/ https://www.ncbi.nlm.nih.gov/pubmed/25309517 http://dx.doi.org/10.3389/fmicb.2014.00477 |