Cargando…
Automated synthesis of backbone protected peptides
The synthesis of peptides rich in aggregation prone sequences can be improved with backbone protection. We report the automated introduction of backbone protection to a peptide. This new method was applied in a fully-automated synthesis, giving improved handling, quality and yield of several challen...
Autores principales: | Abdel-Aal, Abu-Baker M., Papageorgiou, George, Quibell, Martin, Offer, John |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161149/ https://www.ncbi.nlm.nih.gov/pubmed/24938489 http://dx.doi.org/10.1039/c4cc03065f |
Ejemplares similares
-
A backbone amide protecting group for overcoming difficult sequences and suppressing aspartimide formation
por: Abdel‐Aal, Abu‐Baker M., et al.
Publicado: (2016) -
Methodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening Technologies
por: Shinbara, Koki, et al.
Publicado: (2020) -
HF‐Free Boc Synthesis of Peptide Thioesters for Ligation and Cyclization
por: Raz, Richard, et al.
Publicado: (2016) -
Convenient and Scalable Synthesis of Fmoc-Protected Peptide Nucleic Acid Backbone
por: Feagin, Trevor A., et al.
Publicado: (2012) -
Automated Peptide Synthesizers and Glycoprotein Synthesis
por: Tian, Jiekang, et al.
Publicado: (2022)