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Automated synthesis of backbone protected peptides

The synthesis of peptides rich in aggregation prone sequences can be improved with backbone protection. We report the automated introduction of backbone protection to a peptide. This new method was applied in a fully-automated synthesis, giving improved handling, quality and yield of several challen...

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Detalles Bibliográficos
Autores principales: Abdel-Aal, Abu-Baker M., Papageorgiou, George, Quibell, Martin, Offer, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161149/
https://www.ncbi.nlm.nih.gov/pubmed/24938489
http://dx.doi.org/10.1039/c4cc03065f

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