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Human Toll-Like Receptor 8-Selective Agonistic Activities in 1-Alkyl-1H-benzimidazol-2-amines

[Image: see text] Toll-like receptor (TLR)-8 agonists strongly induce the production of T helper 1-polarizing cytokines and may therefore serve as promising candidate vaccine adjuvants, especially for the very young and the elderly. Earlier structure-based ligand design led to the identification of...

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Detalles Bibliográficos
Autores principales:	Beesu, Mallesh, Malladi, Subbalakshmi S., Fox, Lauren M., Jones, Cassandra D., Dixit, Anshuman, David, Sunil A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161153/ https://www.ncbi.nlm.nih.gov/pubmed/25102141 http://dx.doi.org/10.1021/jm500701q

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