Cargando…

Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder

Allopregnanolone and its equipotent stereoisomer, pregnanolone (together termed ALLO), are neuroactive steroids that positively and allosterically modulate the action of gamma-amino-butyric acid (GABA) at GABA(A) receptors. Levels of ALLO are reduced in the cerebrospinal fluid of female premenopausa...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinna, Graziano, Rasmusson, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161165/
https://www.ncbi.nlm.nih.gov/pubmed/25309317
http://dx.doi.org/10.3389/fncel.2014.00256