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Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder

Allopregnanolone and its equipotent stereoisomer, pregnanolone (together termed ALLO), are neuroactive steroids that positively and allosterically modulate the action of gamma-amino-butyric acid (GABA) at GABA(A) receptors. Levels of ALLO are reduced in the cerebrospinal fluid of female premenopausa...

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Detalles Bibliográficos
Autores principales:	Pinna, Graziano, Rasmusson, Ann M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161165/ https://www.ncbi.nlm.nih.gov/pubmed/25309317 http://dx.doi.org/10.3389/fncel.2014.00256

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