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IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by Yersinia pestis Type III Effector YopM

YopM is a leucine-rich repeat (LRR)-containing effector in several Yersinia species, including Yersinia pestis and Y. pseudotuberculosis. Different Yersinia strains encode distinct YopM isoforms with variable numbers of LRRs but conserved C-terminal tails. A 15-LRR isoform in Y. pseudotuberculosis Y...

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Detalles Bibliográficos
Autores principales:	Chung, Lawton K., Philip, Naomi H., Schmidt, Valentina A., Koller, Antonius, Strowig, Till, Flavell, Richard A., Brodsky, Igor E., Bliska, James B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161239/ https://www.ncbi.nlm.nih.gov/pubmed/24987096 http://dx.doi.org/10.1128/mBio.01402-14

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