Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells

Apoptotic cell death is an important response to genotoxic stress that prevents oncogenesis. It is known that tissues can differ in their apoptotic response, but molecular mechanisms are little understood. Here, we show that Drosophila polyploid endocycling cells (G/S cycle) repress the apoptotic re...

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Detalles Bibliográficos
Autores principales: Zhang, Bingqing, Mehrotra, Sonam, Ng, Wei Lun, Calvi, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161308/
https://www.ncbi.nlm.nih.gov/pubmed/25211335
http://dx.doi.org/10.1371/journal.pgen.1004581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161308/
https://www.ncbi.nlm.nih.gov/pubmed/25211335
http://dx.doi.org/10.1371/journal.pgen.1004581

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