Cargando…
Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells
Apoptotic cell death is an important response to genotoxic stress that prevents oncogenesis. It is known that tissues can differ in their apoptotic response, but molecular mechanisms are little understood. Here, we show that Drosophila polyploid endocycling cells (G/S cycle) repress the apoptotic re...
Autores principales: | Zhang, Bingqing, Mehrotra, Sonam, Ng, Wei Lun, Calvi, Brian R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161308/ https://www.ncbi.nlm.nih.gov/pubmed/25211335 http://dx.doi.org/10.1371/journal.pgen.1004581 |
Ejemplares similares
-
Premature endocycling of Drosophila follicle cells causes pleiotropic defects in oogenesis
por: Herriage, Hunter C., et al.
Publicado: (2023) -
Chromatin dysregulation by mutant p53
por: Pfister, Neil T., et al.
Publicado: (2016) -
The p53 control of apoptosis and proliferation: lessons from Drosophila
por: Mollereau, Bertrand, et al.
Publicado: (2014) -
p53-Dependent Repression: DREAM or Reality?
por: Peuget, Sylvain, et al.
Publicado: (2021) -
GFI1 Is Repressed by p53 and Inhibits DNA Damage-Induced Apoptosis
por: Du, Pei, et al.
Publicado: (2013)