Rejuvenation of Meiotic Cohesion in Oocytes during Prophase I Is Required for Chiasma Maintenance and Accurate Chromosome Segregation

Chromosome segregation errors in human oocytes are the leading cause of birth defects, and the risk of aneuploid pregnancy increases dramatically as women age. Accurate segregation demands that sister chromatid cohesion remain intact for decades in human oocytes, and gradual loss of the original coh...

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Detalles Bibliográficos
Autores principales: Weng, Katherine A., Jeffreys, Charlotte A., Bickel, Sharon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161318/
https://www.ncbi.nlm.nih.gov/pubmed/25211017
http://dx.doi.org/10.1371/journal.pgen.1004607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161318/
https://www.ncbi.nlm.nih.gov/pubmed/25211017
http://dx.doi.org/10.1371/journal.pgen.1004607

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