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Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the CDC123/CAMK1D Type 2 Diabetes GWAS Locus

Many of the type 2 diabetes loci identified through genome-wide association studies localize to non-protein-coding intronic and intergenic regions and likely contain variants that regulate gene transcription. The CDC123/CAMK1D type 2 diabetes association signal on chromosome 10 spans an intergenic r...

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Detalles Bibliográficos
Autores principales: Fogarty, Marie P., Cannon, Maren E., Vadlamudi, Swarooparani, Gaulton, Kyle J., Mohlke, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161327/
https://www.ncbi.nlm.nih.gov/pubmed/25211022
http://dx.doi.org/10.1371/journal.pgen.1004633