Cargando…

Interrelationships between ALOX5AP Polymorphisms, Serum Leukotriene B4 Level and Risk of Acute Coronary Syndrome

BACKGROUND: We investigated the relationships between the ALOX5AP gene rs10507391 and rs4769874 polymorphisms, serum levels of leukotriene (LT) B4, and risk of acute coronary syndrome (ACS). METHODS: A total of 709 participants, comprising 508 ACS patients (ACS group) and 201 noncoronary artery dise...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Guoping, Ye, Shan, Hui, Jingjiao, Shen, Dandan, Qi, Chuanping, Xu, Lianhong, Qian, Yichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161330/ https://www.ncbi.nlm.nih.gov/pubmed/25210744 http://dx.doi.org/10.1371/journal.pone.0106596

Ejemplares similares

Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis
por: Ström, Jakob O, et al.
Publicado: (2012)

Leukotriene-related Gene Polymorphisms in Patients with Aspirin-intolerant Urticaria and Aspirin-intolerant Asthma: Differing Contributions of ALOX5 Polymorphism in Korean Population
por: Kim, Seung-Hyun, et al.
Publicado: (2005)

ALOX5AP is a new prognostic indicator in acute myeloid leukemia
por: Chen, Xin-Yi, et al.
Publicado: (2023)

The Interrelationship between Leukotriene B4 and Leukotriene-A4-Hydrolase in Collagen/Adjuvant-Induced Arthritis in Rats
por: Mendes, Mariana Trivilin, et al.
Publicado: (2014)

Association of ALOX5AP gene single nucleotide polymorphisms and cerebral infarction in the Han population of northern China
por: Zhang, Shuang-yan, et al.
Publicado: (2012)

Ferroptosis-Related APOE, BCL3 and ALOX5AP Gene Polymorphisms are Associated with the Risk of Thyroid Cancer
por: Xiao, Zhifu, et al.
Publicado: (2022)

Lack of association between ALOX5AP genetic polymorphisms and risk of ischemic stroke: evidence from meta-analyses
por: Zheng, Jing-Hui, et al.
Publicado: (2019)

Association between the polymorphism (rs17222919, −1316T/G) of 5-lipoxygenase-activating protein gene (ALOX5AP) and the risk of stroke: A meta analysis
por: Ye, Hui, et al.
Publicado: (2018)

The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers
por: Tulah, Asif S, et al.
Publicado: (2011)

ALOX5AP Predicts Poor Prognosis by Enhancing M2 Macrophages Polarization and Immunosuppression in Serous Ovarian Cancer Microenvironment
por: Ye, Xiang, et al.
Publicado: (2021)

Genetic Variants in the Transcriptional Regulatory Region of the ALOX5AP gene and Susceptibility to Ischemic Stroke in Chinese Populations
por: Yang, Dongzhi, et al.
Publicado: (2016)

Hydroperoxidation of Docosahexaenoic Acid by Human ALOX12 and pigALOX15-mini-LOX
por: Canyelles-Niño, Miquel, et al.
Publicado: (2023)

A Promoter Polymorphism (rs17222919, −1316T/G) of ALOX5AP Gene Is Associated with Decreased Risk of Ischemic Stroke in Two Independent Chinese Populations
por: Fan, Yujia, et al.
Publicado: (2015)

Epigenetic regulation mechanism of DNA methylation and miRNAs on the expression of the ALOX5AP gene in patients with ischemic stroke
por: Bie, Xiaoshuai, et al.
Publicado: (2021)

Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients
por: Hotz, Alrun, et al.
Publicado: (2021)

Association between Sex-Related ALOX5 Gene Polymorphisms and Lung Atopy Risk
por: Mirra, Davida, et al.
Publicado: (2023)

Influence of leukotriene gene polymorphisms on chronic rhinosinusitis
por: Al-Shemari, Hasan, et al.
Publicado: (2008)

Variants of the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and risk of ischemic stroke in Han Chinese of eastern China()
por: Wang, Gannan, et al.
Publicado: (2011)

Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter
por: Heydeck, Dagmar, et al.
Publicado: (2023)

ALOX5AP suppresses osteosarcoma progression via Wnt/β-catenin/EMT pathway and associates with clinical prognosis and immune infiltration
por: Han, Guo-Dong, et al.
Publicado: (2023)

Role of Leukotrienes and Leukotriene Modifiers in Asthma
por: Montuschi, Paolo
Publicado: (2010)

Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population
por: Kim, Tae, et al.
Publicado: (2010)

Targeting Circulating lncRNA ENST00000538705.1 Relieves Acute Coronary Syndrome via Modulating ALOX15
por: Chen, Hao, et al.
Publicado: (2022)

Genetic contribution of the leukotriene pathway to coronary artery disease
por: Hartiala, Jaana, et al.
Publicado: (2011)

ALOX12 polymorphisms are associated with fat mass but not peak bone mineral density in Chinese nuclear families
por: Xiao, W-J, et al.
Publicado: (2011)

Conformational Heterogeneity and Cooperative Effects of Mammalian ALOX15
por: Ivanov, Igor, et al.
Publicado: (2021)

Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5(−/−) Mice
por: Marbach-Breitrück, Eugenia, et al.
Publicado: (2021)

ALOX5, LPA, MMP9 and TPO gene polymorphisms increase atherothrombosis susceptibility in middle-aged Mexicans
por: Camacho-Mejorado, Rafael, et al.
Publicado: (2020)

The interrelationship between metabolic parameters in blood serum of cattle and fertility
por: Sommer, H
Publicado: (1976)

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model
por: Heydeck, Dagmar, et al.
Publicado: (2023)

Correction to ‘ALOX5, LPA, MMP9 and TPO gene polymorphisms increase atherothrombosis susceptibility in middle-aged Mexicans’
por: Camacho-Mejorado, Rafael, et al.
Publicado: (2020)

Nutrition—Disease Interrelationships
por: Cheeke, Peter R.
Publicado: (1987)

Leukotriene generation by eosinophils
Publicado: (1982)

Leukotrienes and kidney diseases
por: Rubinstein, Menachem, et al.
Publicado: (2018)

Leukotriene Antagonists in Dermatology
por: Bubna, Aditya Kumar
Publicado: (2021)

Theoretical Characterization of the Step-by-Step Mechanism of Conversion of Leukotriene A(4) to Leukotriene B(4) Catalysed by the Enzyme Leukotriene A(4) Hydrolase
por: Canyelles-Niño, Miquel, et al.
Publicado: (2022)

Pinosylvin exacerbates LPS-induced apoptosis via ALOX 15 upregulation in leukocytes
por: Kwon, Ohseong, et al.
Publicado: (2018)

Effect of AlOx protection layer on AgNWs for flexible transparent heater
por: Lee, Joon-Min, et al.
Publicado: (2020)

Methylated HNRNPK acts on RPS19 to regulate ALOX15 synthesis in erythropoiesis
por: Naarmann-de Vries, Isabel S, et al.
Publicado: (2021)

Hypermethylation of the ALOX12 and CBS promoters in osteoporosis: Potential biomarkers for early diagnosis
por: Guo, Shang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j0fl5fhg83ejqcgk1tts9fbvf6