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Beta-1 Adrenergic Agonist Treatment Mitigates Negative Changes in Cancellous Bone Microarchitecture and Inhibits Osteocyte Apoptosis during Disuse

The sympathetic nervous system (SNS) plays an important role in mediating bone remodeling. However, the exact role that beta-1 adrenergic receptors (beta1AR) have in this process has not been elucidated. We have previously demonstrated the ability of dobutamine (DOB), primarily a beta1AR agonist, to...

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Detalles Bibliográficos
Autores principales: Swift, Joshua M., Swift, Sibyl N., Allen, Matthew R., Bloomfield, Susan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161377/
https://www.ncbi.nlm.nih.gov/pubmed/25211027
http://dx.doi.org/10.1371/journal.pone.0106904

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