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Retroviral Retention Activates a Syk-Dependent HemITAM in Human Tetherin
Tetherin (BST2/CD317) restricts the release of enveloped viral particles from infected cells. Coupled to this virion retention, hominid tetherins induce proinflammatory gene expression via activating NF-κB. We investigated the events initiating this tetherin-induced signaling and show that physical...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161388/ https://www.ncbi.nlm.nih.gov/pubmed/25211072 http://dx.doi.org/10.1016/j.chom.2014.08.005 |