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Optimization of Mucosal Responses after Intramuscular Immunization with Integrase Defective Lentiviral Vector

Many infectious agents infiltrate the host at the mucosal surfaces and then spread systemically. This implies that an ideal vaccine should induce protective immune responses both at systemic and mucosal sites to counteract invasive mucosal pathogens. We evaluated the in vivo systemic and mucosal ant...

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Detalles Bibliográficos
Autores principales: Rossi, Alessandra, Michelini, Zuleika, Leone, Pasqualina, Borghi, Martina, Blasi, Maria, Bona, Roberta, Spada, Massimo, Grasso, Felicia, Gugliotta, Alessio, Klotman, Mary E., Cara, Andrea, Negri, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161417/
https://www.ncbi.nlm.nih.gov/pubmed/25210766
http://dx.doi.org/10.1371/journal.pone.0107377