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Optimization of Mucosal Responses after Intramuscular Immunization with Integrase Defective Lentiviral Vector
Many infectious agents infiltrate the host at the mucosal surfaces and then spread systemically. This implies that an ideal vaccine should induce protective immune responses both at systemic and mucosal sites to counteract invasive mucosal pathogens. We evaluated the in vivo systemic and mucosal ant...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161417/ https://www.ncbi.nlm.nih.gov/pubmed/25210766 http://dx.doi.org/10.1371/journal.pone.0107377 |