Thyroid Hormone-Regulated Wnt5a/Ror2 Signaling Is Essential for Dedifferentiation of Larval Epithelial Cells into Adult Stem Cells in the Xenopus laevis Intestine

BACKGROUND AND AIMS: Amphibian intestinal remodeling, where thyroid hormone (T3) induces some larval epithelial cells to become adult stem cells analogous to the mammalian intestinal ones, serves as a unique model for studying how the adult stem cells are formed. To clarify its molecular mechanisms,...

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Detalles Bibliográficos
Autores principales: Ishizuya-Oka, Atsuko, Kajita, Mitsuko, Hasebe, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161470/
https://www.ncbi.nlm.nih.gov/pubmed/25211363
http://dx.doi.org/10.1371/journal.pone.0107611

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