Interleukin-6 signaling promotes alternative macrophage activation to limit obesity-associated insulin resistance and endotoxemia

Obesity and insulin resistance are closely associated with the development of low-grade inflammation. Interleukin 6 (IL-6) is linked to obesity-associated inflammation, however its role in this context remains controversial. Here, we show that mice with inactivated Il6ra gene in myeloid cells (Il6ra...

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Detalles Bibliográficos
Autores principales: Mauer, Jan, Chaurasia, Bhagirath, Goldau, Julia, Vogt, Merly C., Ruud, Johan, Nguyen, Khoa D., Theurich, Sebastian, Hausen, A. Christine, Schmitz, Joel, Brönneke, Hella S., Estevez, Emma, Allen, Tamara L., Mesaros, Andrea, Partridge, Linda, Febbraio, Mark A., Chawla, Ajay, Wunderlich, F. Thomas, Brüning, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161471/
https://www.ncbi.nlm.nih.gov/pubmed/24681566
http://dx.doi.org/10.1038/ni.2865

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