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Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies
Pericentrin is a critical centrosomal protein required for organizing pericentriolar material (PCM) in mitosis. Mutations in pericentrin cause the human genetic disorder Majewski/microcephalic osteodysplastic primordial dwarfism type II, making a detailed understanding of its regulation extremely im...
Autores principales: | Galletta, Brian J., Guillen, Rodrigo X., Fagerstrom, Carey J., Brownlee, Chris W., Lerit, Dorothy A., Megraw, Timothy L., Rogers, Gregory C., Rusan, Nasser M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161505/ https://www.ncbi.nlm.nih.gov/pubmed/25031429 http://dx.doi.org/10.1091/mbc.E13-10-0617 |
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