Cargando…
Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism
Oculocutaneous albinism is a group of congenital disorders caused by alterations of melanin biosynthesis. We report our findings in a patient with oculocutaneous albinism who presented with foveal hypoplasia and a foveal hemorrhage. A 48-year-old man noted a dark spot in the middle of the visual fie...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161525/ https://www.ncbi.nlm.nih.gov/pubmed/25228790 http://dx.doi.org/10.2147/OPTH.S68475 |
_version_ | 1782334576489660416 |
---|---|
author | Masuda, Naonori Hasegawa, Taiji Yamashita, Mariko Ogata, Nahoko |
author_facet | Masuda, Naonori Hasegawa, Taiji Yamashita, Mariko Ogata, Nahoko |
author_sort | Masuda, Naonori |
collection | PubMed |
description | Oculocutaneous albinism is a group of congenital disorders caused by alterations of melanin biosynthesis. We report our findings in a patient with oculocutaneous albinism who presented with foveal hypoplasia and a foveal hemorrhage. A 48-year-old man noted a dark spot in the middle of the visual field of his right eye. He had depigmented skin, white hair, white eyebrows, and white cilia. He also had horizontal nystagmus and depigmented irides. His best-corrected visual acuity was 2/100 with −14.0 diopters in the right eye and 3/100 with −5.0 diopters in the left eye. Ophthalmoscopy showed diffuse depigmentation in both eyes and a foveal hemorrhage in the right eye. Optical coherence tomography showed the absence of a foveal pit in both eyes and a subretinal hyperreflective lesion corresponding to the foveal hemorrhage in the right eye. Fluorescein angiography showed that the retinal and choroidal vessels were relatively hypofluorescent because of the lack of a blocking effect of the pigments in the retinal pigment epithelium. Fluorescein angiography and indocyanine green angiography did not show any evidence of choroidal neovascularization in either eye. The foveal hemorrhage in the right eye spontaneously regressed and finally resolved at 3 months after onset. At the final examination, the patient reported that his vision had recovered. A foveal hemorrhage is a rare condition in an eye with foveal hypoplasia associated with albinism. The hemorrhage may be related to high myopia and also to the hypoplasia of the fovea associated with albinism. |
format | Online Article Text |
id | pubmed-4161525 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-41615252014-09-16 Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism Masuda, Naonori Hasegawa, Taiji Yamashita, Mariko Ogata, Nahoko Clin Ophthalmol Case Report Oculocutaneous albinism is a group of congenital disorders caused by alterations of melanin biosynthesis. We report our findings in a patient with oculocutaneous albinism who presented with foveal hypoplasia and a foveal hemorrhage. A 48-year-old man noted a dark spot in the middle of the visual field of his right eye. He had depigmented skin, white hair, white eyebrows, and white cilia. He also had horizontal nystagmus and depigmented irides. His best-corrected visual acuity was 2/100 with −14.0 diopters in the right eye and 3/100 with −5.0 diopters in the left eye. Ophthalmoscopy showed diffuse depigmentation in both eyes and a foveal hemorrhage in the right eye. Optical coherence tomography showed the absence of a foveal pit in both eyes and a subretinal hyperreflective lesion corresponding to the foveal hemorrhage in the right eye. Fluorescein angiography showed that the retinal and choroidal vessels were relatively hypofluorescent because of the lack of a blocking effect of the pigments in the retinal pigment epithelium. Fluorescein angiography and indocyanine green angiography did not show any evidence of choroidal neovascularization in either eye. The foveal hemorrhage in the right eye spontaneously regressed and finally resolved at 3 months after onset. At the final examination, the patient reported that his vision had recovered. A foveal hemorrhage is a rare condition in an eye with foveal hypoplasia associated with albinism. The hemorrhage may be related to high myopia and also to the hypoplasia of the fovea associated with albinism. Dove Medical Press 2014-09-05 /pmc/articles/PMC4161525/ /pubmed/25228790 http://dx.doi.org/10.2147/OPTH.S68475 Text en © 2014 Masuda et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Case Report Masuda, Naonori Hasegawa, Taiji Yamashita, Mariko Ogata, Nahoko Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism |
title | Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism |
title_full | Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism |
title_fullStr | Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism |
title_full_unstemmed | Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism |
title_short | Foveal hemorrhage in an eye with foveal hypoplasia associated with albinism |
title_sort | foveal hemorrhage in an eye with foveal hypoplasia associated with albinism |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161525/ https://www.ncbi.nlm.nih.gov/pubmed/25228790 http://dx.doi.org/10.2147/OPTH.S68475 |
work_keys_str_mv | AT masudanaonori fovealhemorrhageinaneyewithfovealhypoplasiaassociatedwithalbinism AT hasegawataiji fovealhemorrhageinaneyewithfovealhypoplasiaassociatedwithalbinism AT yamashitamariko fovealhemorrhageinaneyewithfovealhypoplasiaassociatedwithalbinism AT ogatanahoko fovealhemorrhageinaneyewithfovealhypoplasiaassociatedwithalbinism |