Cargando…

Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram

The prediction of treatment response in many neuropsychiatric disorders would be facilitated by easily accessible biomarkers. Using flow cytometry, we herein demonstrate correlations between early reductions of p11 levels in Natural Killer (NK) cells and monocytes and antidepressant response to cita...

Descripción completa

Detalles Bibliográficos
Autores principales: Svenningsson, P, Berg, L, Matthews, D, Ionescu, DF, Richards, E, Niciu, M, Malinger, A, Toups, M, Manji, H, Trivedi, MH, Zarate, CA, Greengard, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161667/
https://www.ncbi.nlm.nih.gov/pubmed/24614495
http://dx.doi.org/10.1038/mp.2014.13
_version_ 1782334580073693184
author Svenningsson, P
Berg, L
Matthews, D
Ionescu, DF
Richards, E
Niciu, M
Malinger, A
Toups, M
Manji, H
Trivedi, MH
Zarate, CA
Greengard, P
author_facet Svenningsson, P
Berg, L
Matthews, D
Ionescu, DF
Richards, E
Niciu, M
Malinger, A
Toups, M
Manji, H
Trivedi, MH
Zarate, CA
Greengard, P
author_sort Svenningsson, P
collection PubMed
description The prediction of treatment response in many neuropsychiatric disorders would be facilitated by easily accessible biomarkers. Using flow cytometry, we herein demonstrate correlations between early reductions of p11 levels in Natural Killer (NK) cells and monocytes and antidepressant response to citalopram in patients with major depressive disorder (MDD).
format Online
Article
Text
id pubmed-4161667
institution National Center for Biotechnology Information
language English
publishDate 2014
record_format MEDLINE/PubMed
spelling pubmed-41616672015-03-01 Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram Svenningsson, P Berg, L Matthews, D Ionescu, DF Richards, E Niciu, M Malinger, A Toups, M Manji, H Trivedi, MH Zarate, CA Greengard, P Mol Psychiatry Article The prediction of treatment response in many neuropsychiatric disorders would be facilitated by easily accessible biomarkers. Using flow cytometry, we herein demonstrate correlations between early reductions of p11 levels in Natural Killer (NK) cells and monocytes and antidepressant response to citalopram in patients with major depressive disorder (MDD). 2014-03-11 2014-09 /pmc/articles/PMC4161667/ /pubmed/24614495 http://dx.doi.org/10.1038/mp.2014.13 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Svenningsson, P
Berg, L
Matthews, D
Ionescu, DF
Richards, E
Niciu, M
Malinger, A
Toups, M
Manji, H
Trivedi, MH
Zarate, CA
Greengard, P
Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram
title Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram
title_full Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram
title_fullStr Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram
title_full_unstemmed Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram
title_short Preliminary evidence that early reduction in p11 levels in Natural Killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram
title_sort preliminary evidence that early reduction in p11 levels in natural killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161667/
https://www.ncbi.nlm.nih.gov/pubmed/24614495
http://dx.doi.org/10.1038/mp.2014.13
work_keys_str_mv AT svenningssonp preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT bergl preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT matthewsd preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT ionescudf preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT richardse preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT nicium preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT malingera preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT toupsm preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT manjih preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT trivedimh preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT zarateca preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram
AT greengardp preliminaryevidencethatearlyreductioninp11levelsinnaturalkillercellsandmonocytespredictsthelikelihoodofantidepressantresponsetochroniccitalopram