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Sevoflurane preconditioning ameliorates neuronal deficits by inhibiting microglial MMP-9 expression after spinal cord ischemia/reperfusion in rats

BACKGROUND: Microglia are the primary immune cells of the spinal cord that are activated in response to ischemia/reperfusion (IR) injury and release various neurotrophic and/or neurotoxic factors to determine neuronal survival. Among them, matrix metalloproteinase-9 (MMP-9), which cleaves various co...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Qian, Cao, Xue-Zhao, Wang, Jun, Fang, Bo, Tan, Wen-Fei, Ma, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161899/
https://www.ncbi.nlm.nih.gov/pubmed/25186151
http://dx.doi.org/10.1186/s13041-014-0069-7