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SPONTANEOUS TRANSMEMBRANE HELIX INSERTION THERMODYNAMICALLY MIMICS TRANSLOCON-GUIDED INSERTION

The favorable transfer free energy for a transmembrane (TM) α-helix between the aqueous phase and lipid bilayer underlies the stability of membrane proteins. However, the connection between the energetics and process of membrane protein assembly by the Sec61/SecY translocon complex in vivo is not cl...

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Detalles Bibliográficos
Autores principales:	Ulmschneider, Martin B., Ulmschneider, Jakob P., Schiller, Nina, Wallace, B. A., von Heijne, Gunnar, White, Stephen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161982/ https://www.ncbi.nlm.nih.gov/pubmed/25204588 http://dx.doi.org/10.1038/ncomms5863

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