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The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran

INTRODUCTION: Aflatoxins are secondary toxic metabolites produced by certain group of Aspergillus species in suitable conditions. These toxins are highly toxic, immunosuppressive, mutagenic, teratogenic and carcinogenic metabolites. The purpose of this study was to detection aflatoxin M(1) concentra...

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Autores principales: Rafiei, Hossein, Dehghan, Parvin, Pakshir, Keyvan, Pour, Mostafa Chadegani, Akbari, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162072/
https://www.ncbi.nlm.nih.gov/pubmed/25221755
http://dx.doi.org/10.4103/2277-9175.137859
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author Rafiei, Hossein
Dehghan, Parvin
Pakshir, Keyvan
Pour, Mostafa Chadegani
Akbari, Mojtaba
author_facet Rafiei, Hossein
Dehghan, Parvin
Pakshir, Keyvan
Pour, Mostafa Chadegani
Akbari, Mojtaba
author_sort Rafiei, Hossein
collection PubMed
description INTRODUCTION: Aflatoxins are secondary toxic metabolites produced by certain group of Aspergillus species in suitable conditions. These toxins are highly toxic, immunosuppressive, mutagenic, teratogenic and carcinogenic metabolites. The purpose of this study was to detection aflatoxin M(1) concentration in mother's milk from rural area of Khorrambid town of Fars Province. MATERIALS AND METHODS: In this study, 87 milk samples of mothers were collected by cluster sampling methods in the period between June and July 2011 and the amount of aflatoxin M(1) was measured by a competitive ELISA method. RESULTS: From 87 mother's milk, 24 (27.6%) samples were contaminated with aflatoxin M(1) with mean concentration of 0.56 ± 1.23 pg/ml (range 0.13-4.91 pg/ml). CONCLUSION: The amount of aflatoxin M(1) in mothers’ milk was lower than 50 ng/l (Europe Union and Iranian standard). Detection of Aflatoxin M(1) in mothers’ milk is due to consuming contaminated food. This contamination not only threatens the health of the mothers but also has irreversible effects on the growth and health of their babies.
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spelling pubmed-41620722014-09-14 The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran Rafiei, Hossein Dehghan, Parvin Pakshir, Keyvan Pour, Mostafa Chadegani Akbari, Mojtaba Adv Biomed Res Original Article INTRODUCTION: Aflatoxins are secondary toxic metabolites produced by certain group of Aspergillus species in suitable conditions. These toxins are highly toxic, immunosuppressive, mutagenic, teratogenic and carcinogenic metabolites. The purpose of this study was to detection aflatoxin M(1) concentration in mother's milk from rural area of Khorrambid town of Fars Province. MATERIALS AND METHODS: In this study, 87 milk samples of mothers were collected by cluster sampling methods in the period between June and July 2011 and the amount of aflatoxin M(1) was measured by a competitive ELISA method. RESULTS: From 87 mother's milk, 24 (27.6%) samples were contaminated with aflatoxin M(1) with mean concentration of 0.56 ± 1.23 pg/ml (range 0.13-4.91 pg/ml). CONCLUSION: The amount of aflatoxin M(1) in mothers’ milk was lower than 50 ng/l (Europe Union and Iranian standard). Detection of Aflatoxin M(1) in mothers’ milk is due to consuming contaminated food. This contamination not only threatens the health of the mothers but also has irreversible effects on the growth and health of their babies. Medknow Publications & Media Pvt Ltd 2014-07-31 /pmc/articles/PMC4162072/ /pubmed/25221755 http://dx.doi.org/10.4103/2277-9175.137859 Text en Copyright: © 2014 Rafiei. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Rafiei, Hossein
Dehghan, Parvin
Pakshir, Keyvan
Pour, Mostafa Chadegani
Akbari, Mojtaba
The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran
title The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran
title_full The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran
title_fullStr The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran
title_full_unstemmed The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran
title_short The concentration of aflatoxin M(1) in the mothers’ milk in Khorrambid City, Fars, Iran
title_sort concentration of aflatoxin m(1) in the mothers’ milk in khorrambid city, fars, iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162072/
https://www.ncbi.nlm.nih.gov/pubmed/25221755
http://dx.doi.org/10.4103/2277-9175.137859
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