PTEN deficiency and mutant p53 confer glucose-addiction to thyroid cancer cells: impact of glucose depletion on cell proliferation, cell survival, autophagy and cell migration

Proliferating cancer cells oxidize glucose through the glycolytic pathway. Since this metabolism is less profitable in terms of ATP production, cancer cells consume large quantity of glucose, and those that experience insufficient blood supply become glucose-addicted. We have analyzed the response t...

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Detalles Bibliográficos
Autores principales: Morani, Federica, Phadngam, Suratchanee, Follo, Carlo, Titone, Rossella, Thongrakard, Visa, Galetto, Alessandra, Alabiso, Oscar, Isidoro, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162142/
https://www.ncbi.nlm.nih.gov/pubmed/25221641

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