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Retrotransposition of Long Interspersed Element 1 Induced by Methamphetamine or Cocaine

Long interspersed element 1 (L1) is a retroelement constituting ∼17% of the human genome. A single human cell has 80–100 copies of L1 capable of retrotransposition (L1-RTP), ∼10% of which are “hot L1” copies, meaning they are primed for “jumping” within the genome. Recent studies demonstrated induct...

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Detalles Bibliográficos
Autores principales:	Okudaira, Noriyuki, Ishizaka, Yukihito, Nishio, Hajime
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162154/ https://www.ncbi.nlm.nih.gov/pubmed/25053411 http://dx.doi.org/10.1074/jbc.M114.559419

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