Protein Kinase Cα (PKCα) Regulates Bone Architecture and Osteoblast Activity

Bones' strength is achieved and maintained through adaptation to load bearing. The role of the protein kinase PKCα in this process has not been previously reported. However, we observed a phenotype in the long bones of Prkca(−/−) female but not male mice, in which bone tissue progressively inva...

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Detalles Bibliográficos
Autores principales: Galea, Gabriel L., Meakin, Lee B., Williams, Christopher M., Hulin-Curtis, Sarah L., Lanyon, Lance E., Poole, Alastair W., Price, Joanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162157/
https://www.ncbi.nlm.nih.gov/pubmed/25070889
http://dx.doi.org/10.1074/jbc.M114.580365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162157/
https://www.ncbi.nlm.nih.gov/pubmed/25070889
http://dx.doi.org/10.1074/jbc.M114.580365

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