TrkB overexpression in mice buffers against memory deficits and depression-like behavior but not all anxiety- and stress-related symptoms induced by developmental exposure to methylmercury

Developmental exposure to low dose of methylmercury (MeHg) has a long-lasting effect on memory and attention deficits in humans, as well as cognitive performance, depression-like behavior and the hippocampal levels of the brain-derived neurotrophic factor (Bdnf)in mice. The Bdnf receptor TrkB is a k...

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Detalles Bibliográficos
Autores principales: Karpova, Nina N., Lindholm, Jesse Saku Olavi, Kulesskaya, Natalia, Onishchenko, Natalia, Vahter, Marie, Popova, Dina, Ceccatelli, Sandra, Castrén, Eero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162384/
https://www.ncbi.nlm.nih.gov/pubmed/25309367
http://dx.doi.org/10.3389/fnbeh.2014.00315

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