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Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis

We recently reported that young (3 to 4 months old) mice lacking Exon 1 of the Smad7 gene (S7ΔEx1 mice) show enhanced proliferation of neural stem and progenitor cells (NPCs) in the hippocampal dentate gyrus (DG) and in the subventricular zone (SVZ) of the lateral ventricles. It remained unclear, ho...

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Detalles Bibliográficos
Autores principales:	Marschallinger, Julia, Krampert, Monika, Couillard-Despres, Sebastien, Heuchel, Rainer, Bogdahn, Ulrich, Aigner, Ludwig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162458/ https://www.ncbi.nlm.nih.gov/pubmed/24862634 http://dx.doi.org/10.1016/j.exger.2014.05.011

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