Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer

The antiestrogen tamoxifen is a well-tolerated, effective treatment for estrogen receptor-α-positive (ER+) breast cancer, but development of resistance eventually limits its use. Here we show that expression of MAGEA2, and related members of this cancer-testis antigen family, is upregulated in tamox...

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Detalles Bibliográficos
Autores principales: Wong, P-P, Yeoh, C C, Ahmad, A S, Chelala, C, Gillett, C, Speirs, V, Jones, J L, Hurst, H C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162461/
https://www.ncbi.nlm.nih.gov/pubmed/24662835
http://dx.doi.org/10.1038/onc.2014.45

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