Osteocyte expression of caspase-3, COX-2, IL-6 and sclerostin are spatially and temporally associated following stress fracture initiation

Stress fractures (SFxs) are debilitating injuries and exact mechanisms that initiate their repair incompletely understood. We hypothesised that osteocyte apoptosis and expression of cytokines and proteins such as sclerostin, VEGF, TGF-β, COX-2 and IL-6 were early signalling events to facilitate the...

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Detalles Bibliográficos
Autores principales: Wu, Andy C, Kidd, Lisa J, Cowling, Nicholas R, Kelly, Wendy L, Forwood, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162464/
https://www.ncbi.nlm.nih.gov/pubmed/25228984
http://dx.doi.org/10.1038/bonekey.2014.66

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