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Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats
Current treatments for depression, including serotonin-specific reuptake inhibitors (SSRIs), are only partially effective, with a high incidence of residual symptoms, relapse, and treatment resistance. Loss of cognitive flexibility, a component of depression, is associated with dysregulation of the...
Autores principales: | Wallace, Ashley, Pehrson, Alan L., Sánchez, Connie, Morilak, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162520/ https://www.ncbi.nlm.nih.gov/pubmed/24852131 http://dx.doi.org/10.1017/S1461145714000571 |
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