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Diminished Neurogenic Femoral Artery Vasoconstrictor Response in a Zucker Obese Rat Model: Differential Regulation of NOS and COX Derivatives

OBJECTIVE: Peripheral arterial disease is one of the macrovascular complications of type 2 diabetes mellitus. This study addresses femoral artery regulation in a prediabetic model of obese Zucker rats (OZR) by examining cross-talk between endothelial and neural factors. METHODS AND RESULTS: Arterial...

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Detalles Bibliográficos
Autores principales: Martínez, Ana Cristina, Hernández, Medardo, Novella, Susana, Martínez, María Pilar, Pagán, Rosa María, Hermenegildo, Carlos, García-Sacristán, Albino, Prieto, Dolores, Benedito, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162543/
https://www.ncbi.nlm.nih.gov/pubmed/25216050
http://dx.doi.org/10.1371/journal.pone.0106372