The Role of Oxidoreductases in Determining the Function of the Neisserial Lipid A Phosphoethanolamine Transferase Required for Resistance to Polymyxin

The decoration of the lipid A headgroups of the lipooligosaccharide (LOS) by the LOS phosphoethanolamine (PEA) transferase (LptA) in Neisseria spp. is central for resistance to polymyxin. The structure of the globular domain of LptA shows that the protein has five disulphide bonds, indicating that i...

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Detalles Bibliográficos
Autores principales: Piek, Susannah, Wang, Zhirui, Ganguly, Jhuma, Lakey, Adam M., Bartley, Stephanie N., Mowlaboccus, Shakeel, Anandan, Anandhi, Stubbs, Keith A., Scanlon, Martin J., Vrielink, Alice, Azadi, Parastoo, Carlson, Russell W., Kahler, Charlene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162559/
https://www.ncbi.nlm.nih.gov/pubmed/25215579
http://dx.doi.org/10.1371/journal.pone.0106513

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