Lung Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis Exhibit Genome-Wide Differences in DNA Methylation Compared to Fibroblasts from Nonfibrotic Lung

Excessive fibroproliferation is a central hallmark of idiopathic pulmonary fibrosis (IPF), a chronic, progressive disorder that results in impaired gas exchange and respiratory failure. Fibroblasts are the key effector cells in IPF, and aberrant expression of multiple genes contributes to their exce...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Steven K., Scruggs, Anne M., McEachin, Richard C., White, Eric S., Peters-Golden, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162578/
https://www.ncbi.nlm.nih.gov/pubmed/25215577
http://dx.doi.org/10.1371/journal.pone.0107055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162578/
https://www.ncbi.nlm.nih.gov/pubmed/25215577
http://dx.doi.org/10.1371/journal.pone.0107055

Ejemplares similares