Lung Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis Exhibit Genome-Wide Differences in DNA Methylation Compared to Fibroblasts from Nonfibrotic Lung

Excessive fibroproliferation is a central hallmark of idiopathic pulmonary fibrosis (IPF), a chronic, progressive disorder that results in impaired gas exchange and respiratory failure. Fibroblasts are the key effector cells in IPF, and aberrant expression of multiple genes contributes to their exce...

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Detalles Bibliográficos
Autores principales: Huang, Steven K., Scruggs, Anne M., McEachin, Richard C., White, Eric S., Peters-Golden, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162578/
https://www.ncbi.nlm.nih.gov/pubmed/25215577
http://dx.doi.org/10.1371/journal.pone.0107055

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