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An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines

BACKGROUND: SOX2 is a core component of the transcriptional network responsible for maintaining embryonal carcinoma cells (ECCs) in a pluripotent, undifferentiated state of self-renewal. As such, SOX2 is an oncogenic transcription factor and crucial cancer stem cell (CSC) biomarker in embryonal carc...

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Detalles Bibliográficos
Autores principales:	Vencken, Sebastian F, Sethupathy, Praveen, Blackshields, Gordon, Spillane, Cathy, Elbaruni, Salah, Sheils, Orla, Gallagher, Michael F, O’Leary, John J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162954/ https://www.ncbi.nlm.nih.gov/pubmed/25156079 http://dx.doi.org/10.1186/1471-2164-15-711

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