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Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study

BACKGROUND: International studies on the association between maternal body mass index (BMI) and spontaneous preterm birth (PTB) yield controversial results warranting large studies from other settings. The aim of this article was to study association between maternal early pregnancy BMI and the risk...

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Autores principales: Sharashova, Ekaterina E, Anda, Erik E, Grjibovski, Andrej M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162961/
https://www.ncbi.nlm.nih.gov/pubmed/25192943
http://dx.doi.org/10.1186/1471-2393-14-303
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author Sharashova, Ekaterina E
Anda, Erik E
Grjibovski, Andrej M
author_facet Sharashova, Ekaterina E
Anda, Erik E
Grjibovski, Andrej M
author_sort Sharashova, Ekaterina E
collection PubMed
description BACKGROUND: International studies on the association between maternal body mass index (BMI) and spontaneous preterm birth (PTB) yield controversial results warranting large studies from other settings. The aim of this article was to study association between maternal early pregnancy BMI and the risk of spontaneous PTB in Murmansk County (MC), Northwest Russia. METHODS: This is a registry-based cohort study. All women with singleton pregnancies registered at antenatal clinics during the first 12 weeks of gestation and who delivered in MC between January, 1(st) 2006 and December, 31(st) 2011 comprised the study base (n = 29,709). All women were categorized by BMI into four groups: underweight (<18.5 kg/m(2)), normal (18.5–24.9 kg/m(2)), overweight (25.0–29.9 kg/m(2)), and obese (≥30.0 kg/m(2)). Multivariable logistic regression was used to study associations between maternal BMI and PTB (<37 weeks) and very preterm birth (VPTB) (<32 weeks) adjusted for socio-economic factors, biological and lifestyle characteristics. RESULTS: The prevalence of underweight, overweight and obesity were 7.1% (95% CI: 6.8-7.4), 18.3% (95% CI: 17.8-18.7) and 7.1% (95% CI: 6.8-7.4), respectively. Altogether, 5.5% (95% CI: 5.3-5.8) of the births were PTB and 0.8% (95% CI: 0.7-0.9) were VPTB. After adjustment, both underweight (OR = 1.25, 95% CI: 1.03-1.50), overweight (OR = 1.10, 95% CI: 0.97-1.26) and obese (OR = 1.31, 95% CI: 1.08-1.57) women were more likely to deliver preterm. VPTB was associated with overweight (OR = 1.47, 95% CI: 1.056-2.03) and obesity (OR = 1.63, 95% CI: 1.02-2.60). CONCLUSION: The findings demonstrate a J-shaped association between first trimester maternal BMI and spontaneous PTB and VPTB with increased risk among underweight, overweight and obese women.
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spelling pubmed-41629612014-09-14 Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study Sharashova, Ekaterina E Anda, Erik E Grjibovski, Andrej M BMC Pregnancy Childbirth Research Article BACKGROUND: International studies on the association between maternal body mass index (BMI) and spontaneous preterm birth (PTB) yield controversial results warranting large studies from other settings. The aim of this article was to study association between maternal early pregnancy BMI and the risk of spontaneous PTB in Murmansk County (MC), Northwest Russia. METHODS: This is a registry-based cohort study. All women with singleton pregnancies registered at antenatal clinics during the first 12 weeks of gestation and who delivered in MC between January, 1(st) 2006 and December, 31(st) 2011 comprised the study base (n = 29,709). All women were categorized by BMI into four groups: underweight (<18.5 kg/m(2)), normal (18.5–24.9 kg/m(2)), overweight (25.0–29.9 kg/m(2)), and obese (≥30.0 kg/m(2)). Multivariable logistic regression was used to study associations between maternal BMI and PTB (<37 weeks) and very preterm birth (VPTB) (<32 weeks) adjusted for socio-economic factors, biological and lifestyle characteristics. RESULTS: The prevalence of underweight, overweight and obesity were 7.1% (95% CI: 6.8-7.4), 18.3% (95% CI: 17.8-18.7) and 7.1% (95% CI: 6.8-7.4), respectively. Altogether, 5.5% (95% CI: 5.3-5.8) of the births were PTB and 0.8% (95% CI: 0.7-0.9) were VPTB. After adjustment, both underweight (OR = 1.25, 95% CI: 1.03-1.50), overweight (OR = 1.10, 95% CI: 0.97-1.26) and obese (OR = 1.31, 95% CI: 1.08-1.57) women were more likely to deliver preterm. VPTB was associated with overweight (OR = 1.47, 95% CI: 1.056-2.03) and obesity (OR = 1.63, 95% CI: 1.02-2.60). CONCLUSION: The findings demonstrate a J-shaped association between first trimester maternal BMI and spontaneous PTB and VPTB with increased risk among underweight, overweight and obese women. BioMed Central 2014-09-04 /pmc/articles/PMC4162961/ /pubmed/25192943 http://dx.doi.org/10.1186/1471-2393-14-303 Text en © Sharashova et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Sharashova, Ekaterina E
Anda, Erik E
Grjibovski, Andrej M
Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study
title Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study
title_full Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study
title_fullStr Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study
title_full_unstemmed Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study
title_short Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study
title_sort early pregnancy body mass index and spontaneous preterm birth in northwest russia: a registry-based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162961/
https://www.ncbi.nlm.nih.gov/pubmed/25192943
http://dx.doi.org/10.1186/1471-2393-14-303
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