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Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass

BACKGROUND: Anastomotic leak is one of the most serious complications following bariatric laparoscopic Roux-en-Y gastric bypass (LRYGB), and associated with high morbidity rates and prolonged hospital stay. Timely management is of utmost importance for the clinical outcome. This study evaluated the...

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Autores principales: Jacobsen, H J, Nergard, B J, Leifsson, B G, Frederiksen, S G, Agajahni, E, Ekelund, M, Hedenbro, J, Gislason, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163000/
https://www.ncbi.nlm.nih.gov/pubmed/24536012
http://dx.doi.org/10.1002/bjs.9388
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author Jacobsen, H J
Nergard, B J
Leifsson, B G
Frederiksen, S G
Agajahni, E
Ekelund, M
Hedenbro, J
Gislason, H
author_facet Jacobsen, H J
Nergard, B J
Leifsson, B G
Frederiksen, S G
Agajahni, E
Ekelund, M
Hedenbro, J
Gislason, H
author_sort Jacobsen, H J
collection PubMed
description BACKGROUND: Anastomotic leak is one of the most serious complications following bariatric laparoscopic Roux-en-Y gastric bypass (LRYGB), and associated with high morbidity rates and prolonged hospital stay. Timely management is of utmost importance for the clinical outcome. This study evaluated the approach to suspected leakage in a high-volume bariatric surgery unit. METHODS: All consecutive patients who underwent LRYGB performed by the same team of surgeons were registered prospectively in a clinical database from September 2005 to June 2012. Suspected leaks were identified based on either clinical suspicion and/or associated laboratory values, or by a complication severity grade of at least II using the Clavien–Dindo score. RESULTS: A total of 6030 patients underwent LRYGB during the study period. The leakage rate was 1·1 per cent (64 patients). Forty-five leaks (70 per cent) were treated surgically and 19 (30 per cent) conservatively. Eight (13 per cent) of 64 patients needed intensive care and the mortality rate was 3 per cent (2 of 64). Early leaks (developing in 5 days or fewer after LRYGB) were treated by suture of the defect in 20 of 22 patients and/or operative drainage in 13. Late leaks (after 5 days) were managed with operative drainage in 19 of 23 patients and insertion of a gastrostomy tube in 15. Patients who underwent surgical treatment early after the symptoms of leakage developed had a shorter hospital stay than those who had symptoms for more than 24 h before reoperation (12·5 versus 24·4 days respectively; P < 0·001). CONCLUSION: Clinical suspicion of an anastomotic leak should prompt an aggressive surgical approach without undue delay. Early operative treatment was associated with shorter hospital stay. Delays in treatment, including patient delay, after symptom development were associated with adverse outcomes.
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spelling pubmed-41630002014-09-22 Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass Jacobsen, H J Nergard, B J Leifsson, B G Frederiksen, S G Agajahni, E Ekelund, M Hedenbro, J Gislason, H Br J Surg Original Articles BACKGROUND: Anastomotic leak is one of the most serious complications following bariatric laparoscopic Roux-en-Y gastric bypass (LRYGB), and associated with high morbidity rates and prolonged hospital stay. Timely management is of utmost importance for the clinical outcome. This study evaluated the approach to suspected leakage in a high-volume bariatric surgery unit. METHODS: All consecutive patients who underwent LRYGB performed by the same team of surgeons were registered prospectively in a clinical database from September 2005 to June 2012. Suspected leaks were identified based on either clinical suspicion and/or associated laboratory values, or by a complication severity grade of at least II using the Clavien–Dindo score. RESULTS: A total of 6030 patients underwent LRYGB during the study period. The leakage rate was 1·1 per cent (64 patients). Forty-five leaks (70 per cent) were treated surgically and 19 (30 per cent) conservatively. Eight (13 per cent) of 64 patients needed intensive care and the mortality rate was 3 per cent (2 of 64). Early leaks (developing in 5 days or fewer after LRYGB) were treated by suture of the defect in 20 of 22 patients and/or operative drainage in 13. Late leaks (after 5 days) were managed with operative drainage in 19 of 23 patients and insertion of a gastrostomy tube in 15. Patients who underwent surgical treatment early after the symptoms of leakage developed had a shorter hospital stay than those who had symptoms for more than 24 h before reoperation (12·5 versus 24·4 days respectively; P < 0·001). CONCLUSION: Clinical suspicion of an anastomotic leak should prompt an aggressive surgical approach without undue delay. Early operative treatment was associated with shorter hospital stay. Delays in treatment, including patient delay, after symptom development were associated with adverse outcomes. John Wiley & Sons, Ltd 2014-03 2014-02-17 /pmc/articles/PMC4163000/ /pubmed/24536012 http://dx.doi.org/10.1002/bjs.9388 Text en © 2014 The Authors. BJS published by John Wiley & Sons Ltd on behalf of BJS Society Ltd. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Jacobsen, H J
Nergard, B J
Leifsson, B G
Frederiksen, S G
Agajahni, E
Ekelund, M
Hedenbro, J
Gislason, H
Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass
title Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass
title_full Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass
title_fullStr Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass
title_full_unstemmed Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass
title_short Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-y gastric bypass
title_sort management of suspected anastomotic leak after bariatric laparoscopic roux-en-y gastric bypass
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163000/
https://www.ncbi.nlm.nih.gov/pubmed/24536012
http://dx.doi.org/10.1002/bjs.9388
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