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Describing the genetic architecture of epilepsy through heritability analysis

Epilepsy is a disease with substantial missing heritability; despite its high genetic component, genetic association studies have had limited success detecting common variants which influence susceptibility. In this paper, we reassess the role of common variants on epilepsy using extensions of herit...

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Detalles Bibliográficos
Autores principales: Speed, Doug, O’Brien, Terence J., Palotie, Aarno, Shkura, Kirill, Marson, Anthony G., Balding, David J., Johnson, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163034/
https://www.ncbi.nlm.nih.gov/pubmed/25063994
http://dx.doi.org/10.1093/brain/awu206