Cargando…
Describing the genetic architecture of epilepsy through heritability analysis
Epilepsy is a disease with substantial missing heritability; despite its high genetic component, genetic association studies have had limited success detecting common variants which influence susceptibility. In this paper, we reassess the role of common variants on epilepsy using extensions of herit...
Autores principales: | Speed, Doug, O’Brien, Terence J., Palotie, Aarno, Shkura, Kirill, Marson, Anthony G., Balding, David J., Johnson, Michael R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163034/ https://www.ncbi.nlm.nih.gov/pubmed/25063994 http://dx.doi.org/10.1093/brain/awu206 |
Ejemplares similares
-
SumHer better estimates the SNP heritability of complex traits from summary statistics
por: Speed, Doug, et al.
Publicado: (2018) -
Re-evaluation of SNP heritability in complex human traits
por: Speed, Doug, et al.
Publicado: (2017) -
Genome-wide association, prediction and heritability in bacteria with application to Streptococcus pneumoniae
por: Mallawaarachchi, Sudaraka, et al.
Publicado: (2022) -
Understanding complex traits: from farmers to pharmas
por: Speed, Doug, et al.
Publicado: (2012) -
MultiBLUP: improved SNP-based prediction for complex traits
por: Speed, Doug, et al.
Publicado: (2014)