A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction

BACKGROUND: The HIV-1 accessory proteins, Viral Infectivity Factor (Vif) and the pleiotropic Viral Protein R (Vpr) are important for efficient virus replication. While in non-permissive cells an appropriate amount of Vif is critical to counteract APOBEC3G-mediated host restriction, the Vpr-induced G...

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Detalles Bibliográficos
Autores principales: Widera, Marek, Hillebrand, Frank, Erkelenz, Steffen, Vasudevan, Ananda Ayyappan Jaguva, Münk, Carsten, Schaal, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163160/
https://www.ncbi.nlm.nih.gov/pubmed/25169827
http://dx.doi.org/10.1186/s12977-014-0072-1

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