Recent Trends of Polymer Mediated Liposomal Gene Delivery System

Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated g...

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Autores principales: Kundu, Shyamal Kumar, Sharma, Ashish Ranjan, Lee, Sang-Soo, Sharma, Garima, George Priya Doss, C., Yagihara, Shin, Kim, Do-Young, Nam, Ju-Suk, Chakraborty, Chiranjib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163454/
https://www.ncbi.nlm.nih.gov/pubmed/25250340
http://dx.doi.org/10.1155/2014/934605
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author Kundu, Shyamal Kumar
Sharma, Ashish Ranjan
Lee, Sang-Soo
Sharma, Garima
George Priya Doss, C.
Yagihara, Shin
Kim, Do-Young
Nam, Ju-Suk
Chakraborty, Chiranjib
author_facet Kundu, Shyamal Kumar
Sharma, Ashish Ranjan
Lee, Sang-Soo
Sharma, Garima
George Priya Doss, C.
Yagihara, Shin
Kim, Do-Young
Nam, Ju-Suk
Chakraborty, Chiranjib
author_sort Kundu, Shyamal Kumar
collection PubMed
description Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to depict a portrait about the polymer based liposomal gene delivery systems and their future applications. Herein, we have discussed in detail the characteristics of liposome, importance of polymer for liposome formulation, gene delivery, and future direction of liposome based gene delivery as a whole.
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spelling pubmed-41634542014-09-23 Recent Trends of Polymer Mediated Liposomal Gene Delivery System Kundu, Shyamal Kumar Sharma, Ashish Ranjan Lee, Sang-Soo Sharma, Garima George Priya Doss, C. Yagihara, Shin Kim, Do-Young Nam, Ju-Suk Chakraborty, Chiranjib Biomed Res Int Review Article Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to depict a portrait about the polymer based liposomal gene delivery systems and their future applications. Herein, we have discussed in detail the characteristics of liposome, importance of polymer for liposome formulation, gene delivery, and future direction of liposome based gene delivery as a whole. Hindawi Publishing Corporation 2014 2014-08-27 /pmc/articles/PMC4163454/ /pubmed/25250340 http://dx.doi.org/10.1155/2014/934605 Text en Copyright © 2014 Shyamal Kumar Kundu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kundu, Shyamal Kumar
Sharma, Ashish Ranjan
Lee, Sang-Soo
Sharma, Garima
George Priya Doss, C.
Yagihara, Shin
Kim, Do-Young
Nam, Ju-Suk
Chakraborty, Chiranjib
Recent Trends of Polymer Mediated Liposomal Gene Delivery System
title Recent Trends of Polymer Mediated Liposomal Gene Delivery System
title_full Recent Trends of Polymer Mediated Liposomal Gene Delivery System
title_fullStr Recent Trends of Polymer Mediated Liposomal Gene Delivery System
title_full_unstemmed Recent Trends of Polymer Mediated Liposomal Gene Delivery System
title_short Recent Trends of Polymer Mediated Liposomal Gene Delivery System
title_sort recent trends of polymer mediated liposomal gene delivery system
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163454/
https://www.ncbi.nlm.nih.gov/pubmed/25250340
http://dx.doi.org/10.1155/2014/934605
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