Multiple Analytical Approaches Demonstrate a Complex Relationship of Genetic and Nongenetic Factors with Cisplatin- and Carboplatin-Induced Nephrotoxicity in Lung Cancer Patients

Background. Cisplatin and carboplatin cause nephrotoxicity by forming platinum-DNA adducts and lead to cell death. Methods. One-hundred and sixteen Taiwanese lung cancer patients who received cisplatin or carboplatin more than twice were recruited, and their genotypes were determined. The risk of re...

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Detalles Bibliográficos
Autores principales: Liu, H. Eugene, Bai, Kuan-Jen, Hsieh, Yu-Chen, Yu, Ming-Chih, Lee, Chun-Nin, Chang, Jer-Hua, Hsu, Han-Lin, Lu, Pei-Chih, Chen, Hsiang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163485/
https://www.ncbi.nlm.nih.gov/pubmed/25250341
http://dx.doi.org/10.1155/2014/937429

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