In vivo characterization of the role of tissue‐specific translation elongation factor 1A2 in protein synthesis reveals insights into muscle atrophy

Translation elongation factor 1A2 (eEF1A2), uniquely among translation factors, is expressed specifically in neurons and muscle. eEF1A2‐null mutant wasted mice develop an aggressive, early‐onset form of neurodegeneration, but it is unknown whether the wasting results from denervation of the muscles,...

Descripción completa

Detalles Bibliográficos
Autores principales: Doig, Jennifer, Griffiths, Lowri A., Peberdy, David, Dharmasaroja, Permphan, Vera, Maria, Davies, Faith J. C., Newbery, Helen J., Brownstein, David, Abbott, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163635/
https://www.ncbi.nlm.nih.gov/pubmed/24460877
http://dx.doi.org/10.1111/febs.12554

Ejemplares similares

Ejemplares similares