N‐methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes

Guanine quadruplexes (GQ) are four‐stranded DNA structures formed by guanine‐rich DNA sequences. The formation of GQs inhibits cancer cell growth, although the detection of GQs in vivo has proven difficult, in part because of their structural diversity. The development of GQ‐selective fluorescent re...

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Detalles Bibliográficos
Autores principales: Sabharwal, Navin C., Savikhin, Victoria, Turek‐Herman, Joshua R., Nicoludis, John M., Szalai, Veronika A., Yatsunyk, Liliya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163640/
https://www.ncbi.nlm.nih.gov/pubmed/24494857
http://dx.doi.org/10.1111/febs.12734

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