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Telomerase reverse transcriptase in the regulation of gene expression

Telomerase plays a pivotal role in the pathology of aging and cancer by maintaining genome integrity, controlling cell proliferation, and regulating tissue homeostasis. Telomerase is essentially composed of an RNA component, Telomerase RNA or TERC, which serves as a template for telomeric DNA synthe...

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Detalles Bibliográficos
Autores principales: Zhou, Junzhi, Ding, Deqiang, Wang, Miao, Cong, Yu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163847/
https://www.ncbi.nlm.nih.gov/pubmed/24388106
http://dx.doi.org/10.5483/BMBRep.2014.47.1.284