Cargando…
Cohesin gene mutations in tumorigenesis: from discovery to clinical significance
Cohesin is a multi-protein complex composed of four core subunits (SMC1A, SMC3, RAD21, and either STAG1 or STAG2) that is responsible for the cohesion of sister chromatids following DNA replication until its cleavage during mitosis thereby enabling faithful segregation of sister chromatids into two...
Autores principales: | Solomon, David A., Kim, Jung-Sik, Waldman, Todd |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163871/ https://www.ncbi.nlm.nih.gov/pubmed/24856830 http://dx.doi.org/10.5483/BMBRep.2014.47.6.092 |
Ejemplares similares
-
USP13 interacts with cohesin and regulates its ubiquitination in human cells
por: He, Xiaoyuan, et al.
Publicado: (2020) -
Characteristics of Cohesin Mutation in Acute Myeloid Leukemia and Its Clinical Significance
por: Han, Caixia, et al.
Publicado: (2021) -
Cohesin mutations in myeloid malignancies: underlying mechanisms
por: Leeke, Bryony, et al.
Publicado: (2014) -
Cohesin Mutations in Cancer: Emerging Therapeutic Targets
por: Antony, Jisha, et al.
Publicado: (2021) -
Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing
por: Hill, Victoria K., et al.
Publicado: (2017)